The Tisch Cancer Institute was established at Mount Sinai Medical Center in December 2007 with the appointment of Steven J. Burakoff, MD as Director. In 2008, a generous gift from Trustee James S. Tisch and his wife, Merryl H. Tisch, created a significant endowment, enabling the naming of the Institute and a vision to create a world class cancer center.

Since its establishment, The Tisch Cancer Institute has:
Recruited more than 30 acclaimed physicians and researchers specializing in basic research, clinical research, and population science
Built outstanding programs in solid tumor oncology
Enhanced existing robust programs in hematological malignancies
Advanced the study of cancer immunology and vaccine therapy
Created a presence in molecular cancer epidemiology

The completion of the Leon and Norma Hess Center for Science and Medicine in 2012 is enabling the recruitment of up to 20 additional cancer researchers on two full research floors, with 48,000 square feet of space dedicated to cancer research. Our outpatient facility, the Derald H. Ruttenberg Treatment Center, has relocated to the Hess building as of October 2012 and now includes 48 examination rooms and 54 infusion suites. The new Ruttenberg Treatment Center augments the Dubin Breast Center, which opened in 2011 and provides a 15,000-square-foot facility for state-of-the-art breast cancer care.